Multiple statistical models reveal specific volatile organic compounds affect sex hormones in American adult male: NHANES 2013–2016

ABSTRACT:

Background

Some VOCs are identified as endocrine-disrupting chemicals (EDCs), interfering with the effect of sex hormones. However, no studies focused on the common spectrum of environmental VOCs exposure affecting sex hormones in the average male population.

Objectives

We aimed to explore the association between VOCs and sex hormones in American adult males using multiple statistical models.

Methods

The generalized linear (GLM), eXtreme Gradient Boosting (XGBoost), weighted quantile sum (WQS), Bayesian kernel machine regression (BKMR) and stratified models were used to evaluate the associations between Specific Volatile Organic Compounds and sex hormones in American adult male from NHANES 2013–2016.

Results

Pearson correlation model revealed the potenti

SUBMITTER: Wei C 

PROVIDER: S-EPMC9877519 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature