SARS-CoV-2 infection during pregnancy and preterm birth in Massachusetts from March 2020 through March 2021.

ABSTRACT:

Background

SARS-CoV-2 infection during pregnancy has been linked to preterm birth, but this association is not well understood.

Objectives

To examine the association between SARS-CoV-2 infection and spontaneous and provider-initiated preterm birth (PTB), and how timing of infection, and race/ethnicity as a marker of structural inequality, may modify this association.

Methods

We conducted a retrospective cohort study among pregnant people who delivered singleton, liveborn infants (22-44 weeks gestation) from 1 March 2020 to 31 March 2021 (n = 68,288). We used Cox proportional hazards models to compare the hazard of PTB between pregnant people with and without laboratory-confirmed SARS-CoV-2 infection during pregnancy. We evaluated this association according to the trim

SUBMITTER: Darling AM 

PROVIDER: S-EPMC9877646 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature