Lupus anticoagulants as a prospective independent predictor in COVID-19 patients.

ABSTRACT:

Objective

Lupus anticoagulant (LA) are commonly detected during SARS-CoV-2 infection. However, the relationship between LA and clinical significance is still unclear.

Methods

A retrospective chart analysis was performed on COVID-19 patients who were tested for LA at our hospital from March 2020 to November 2021. We analyzed the patient's characteristics based on the result of the LA test. In addition, subgroup analysis performed the LA-positive group who had undergone serial LA tests.

Results

A total of 219 COVID-19 patients were enrolled in the study, 148 patients (67.6%) were positive for LA test. The LA-positive group received more treatment of high flow nasal cannula (LA-positive 73.0%, LA-negative 57.7%, p = 0.024). The LA-positive group showed prolonged aPTT, hi

SUBMITTER: Kim H 

PROVIDER: S-EPMC9877696 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature