Safety of coronavirus disease 2019 vaccines in 213 adult patients with sickle cell disease.

ABSTRACT: Given the lack of information about safety of the COVID-19 vaccines for sickle cell disease (SCD) patients, we sought to determine whether COVID-19 vaccine was associated with subsequent hospital admission for vaso-occlusive events (VOEs). We included 402 patients with SCD, including 88 regularly transfused. As of July 31, 2021, 213 (53.0%) of them had received a least one dose of COVID vaccine (Pfizer 93.0%). We showed similar risk of hospital admission for a VOE among vaccinated patients (whether transfused or not) and among a control group of non-vaccinated patients matched for age, sex and genotype.

SUBMITTER: Joseph L 

PROVIDER: S-EPMC9877809 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature