Managing concurrency in cyclical projects under stochastic task environments: Vaccine development projects during pandemics.

ABSTRACT: Aggressive overlapping of stochastic activities during phases of vaccine development has been critical to making effective vaccines for COVID-19 available to the public, at "pandemic" speed. In cyclical projects wherein activities can be overlapped, downstream tasks may need rework on account of having commenced prior to receiving requisite information that is only available upon completion of upstream task(s). We provide a framework to understand the interplay between stochastic overlap duration and rework due to overlap, and its impact on minimizing expected completion time for a cyclical project. We motivate the problem using the new paradigm for planning vaccine development projects. It best exemplifies features and scenarios in our model that were not considered and are also not appar

SUBMITTER: Murthy NN 

PROVIDER: S-EPMC9877995 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature