Hepatic vascular malignancies in children are associated with increased rates of surgical resection and improved overall survival compared with adults.

ABSTRACT:

Background

Hepatic vascular malignancies (HVMs) are rare malignancies, with no standardized treatment regimens. The most common HVMs, angiosarcoma and malignant epithelioid hemangioendothelioma (EHE), are often grouped together in the literature complicating our ability to achieve reliable survival data and treatment strategies.

Objective

To compare the disease characteristics of HVMs, with a subanalysis on pediatric patients.

Methods

The 2016 National Cancer Database was queried for patients with HVMs using international classification of diseases-oncology-3 (ICD-O-3) codes yielding 699 patients. Descriptive statistics, chi-square, Kaplan-Meier, and log-rank analyses were performed.

Results

We found 478 patients (68%) with angiosarcoma and 221 (32%) with EHE.

SUBMITTER: Commander SJ 

PROVIDER: S-EPMC9878303 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature