A comprehensive tool for tumor precision medicine with pharmaco-omics data analysis.

ABSTRACT: Background: Cancer precision medicine is an effective strategy to fight cancers by bridging genomics and drug discovery to provide specific treatment for patients with different genetic characteristics. Although some public databases and modelling frameworks have been developed through studies on drug response, most of them only considered the ramifications of the drug on the cell line and the effects on the patient still require a huge amount of work to integrate data from various databases and calculations, especially concerning precision treatment. Furthermore, not only efficacy but also the adverse effects of drugs on patients should be taken into account during cancer treatment. However, the adverse effects as essential indicators of drug safety assessment are always neglected.

SUBMITTER: Liu Y 

PROVIDER: S-EPMC9878337 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature