Dataset Information

Harnessing the immune system in the treatment of cutaneous T cell lymphomas.

ABSTRACT: Cutaneous T cell lymphomas are a rare subset of non-Hodgkin's lymphomas with predilection for the skin with immunosuppressive effects that drive morbidity and mortality. We are now appreciating that suppression of the immune system is an important step in the progression of disease. It should come as no surprise that therapies historically and currently being used to treat these cancers have immune modulating functions that impact disease outcomes. By understanding the immune effects of our therapies, we may better develop new agents that target the immune system and improve combinatorial treatment strategies to limit morbidity and mortality of these cancers. The immune modulating effect of therapeutic drugs in use and under development for cutaneous T cell lymphomas will be reviewed.

SUBMITTER: Fay CJ

PROVIDER: S-EPMC9878398 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature

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Publications

Harnessing the immune system in the treatment of cutaneous T cell lymphomas.

Fay Christopher J CJ Awh Katherine C KC LeBoeuf Nicole R NR Larocca Cecilia A CA

Frontiers in oncology 20230112

Cutaneous T cell lymphomas are a rare subset of non-Hodgkin's lymphomas with predilection for the skin with immunosuppressive effects that drive morbidity and mortality. We are now appreciating that suppression of the immune system is an important step in the progression of disease. It should come as no surprise that therapies historically and currently being used to treat these cancers have immune modulating functions that impact disease outcomes. By understanding the immune effects of our ther ...[more]

PMID: 36713518

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Dataset Information

Harnessing the immune system in the treatment of cutaneous T cell lymphomas.

Publications

Harnessing the immune system in the treatment of cutaneous T cell lymphomas.

Similar Datasets

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