Lipid Alteration Signature in the Blood Plasma of Individuals With Schizophrenia, Depression, and Bipolar Disorder.

ABSTRACT:

Importance

No clinically applicable diagnostic test exists for severe mental disorders. Lipids harbor potential as disease markers.

Objective

To define a reproducible profile of lipid alterations in the blood plasma of patients with schizophrenia (SCZ) independent of demographic and environmental variables and to investigate its specificity in association with other psychiatric disorders, ie, major depressive disorder (MDD) and bipolar disorder (BPD).

Design, setting, and participants

This was a multicohort case-control diagnostic analysis involving plasma samples from psychiatric patients and control individuals collected between July 17, 2009, and May 18, 2018. Study participants were recruited as consecutive and volunteer samples at multiple inpatient and outpatien

SUBMITTER: Tkachev A 

PROVIDER: S-EPMC9878436 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature