Characteristics and possible mechanisms of metabolic disorder in overweight women with polycystic ovary syndrome.

ABSTRACT:

Background

Polycystic ovary syndrome (PCOS) is a kind of endocrine and metabolic disorder, disturbing the females of reproductive age. Here, we aimed to investigate the metabolic characteristics of overweight women with PCOS and analyze the possible mechanisms.

Methods

We conducted a cross-sectional study on 947 patients with PCOS, who were classified according to body mass index (BMI) as overweight (BMI ≥ 24 kg/m²) or non-overweight (BMI ≤ 23.9 kg/m²). The clinical symptoms, endocrine features, metabolic status, and inflammatory levels of the patients were comprehensively assessed and compared between the patients of the two groups. Additionally, a predictive study on the correlation between inflammation and metabolism was performed using STRING and Cy

SUBMITTER: Yu J 

PROVIDER: S-EPMC9878688 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature