How do common conditions impact health-related quality of life for children? Providing guidance for validating pediatric preference-based measures.

ABSTRACT:

Background

There is increasing interest in the validation of pediatric preference-based health-related quality of life measurement instruments. It is critical that children with various degrees of health-related quality of life (HRQoL) impact are included in validation studies. To inform patient sample selection for validation studies from a pragmatic perspective, this study explored HRQoL impairments between known-groups and HRQoL changes over time across 27 common chronic child health conditions and identified conditions with the largest impact on HRQoL.

Methods

The health dimensions of two common preference-based HRQoL measures, the EQ-5D-Y and CHU9D, were constructed using Pediatric Quality of Life Inventory items that overlap conceptually. Data was from the Longitudinal

SUBMITTER: Xiong X 

PROVIDER: S-EPMC9878815 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature