The probiotic and immunomodulation effects of Limosilactobacillus reuteri RGW1 isolated from calf feces.

ABSTRACT:

Introduction

Limosilactobacillus reuteri is a gut symbiont with multiple remarkable beneficial effects on host health, and members of L. reuteri are valuable probiotic agents. However, L. reuteri showed obvious host specificity.

Methods

In our study, a novel L. reuteri RGW1 was isolated from feces of healthy calves, and its potential as a probiotic candidate were assessed, by combining in vitro, in vivo experiments and genomic analysis.

Results and discussion

RGW1 was sensitive to all the antibiotics tested, and it did not contain any virulence factor-coding genes. This isolate showed good tolerance to acid (pH 3.0), 0.3% bile salt, and simulated gastric fluid. Moreover, this isolate showed a high hydrophobicity index (73.7 ±

SUBMITTER: Huang K 

PROVIDER: S-EPMC9879569 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature