Increased incidence rates of positive blood cultures shortly after chemotherapy compared to radiotherapy among individuals treated for solid malignant tumours.

ABSTRACT:

Background

Cancer treatments suppress immune function and are associated with increased risk of infections, but the overall burden of serious infectious diseases in treated patients has not been clearly elucidated.

Methods

All patients treated for solid malignant tumours with radiotherapy (RT) and/or standard first-line chemotherapy (C) at the Department of Oncology at Rigshospitalet between 01/1/2010 and 31/12/2016 were included. Patients were followed from treatment initiation until the first of new cancer treatment, 1 year after treatment initiation, end of follow-up or death. Incidence rates (IR) of positive blood culture (PBC) per 1000 person-years follow-up (PYFU) were calculated.

Findings

12,433 individuals were included, 3582 (29%), 6349 (51%), and 2502 (20%)

SUBMITTER: Roen A 

PROVIDER: S-EPMC9879832 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature