Ontology highlight
ABSTRACT:
SUBMITTER: Spoutil F
PROVIDER: S-EPMC9879986 | biostudies-literature | 2023 Jan
REPOSITORIES: biostudies-literature
Spoutil Frantisek F Aranaz-Novaliches Goretti G Prochazkova Michaela M Wald Tomas T Novosadova Vendula V Kasparek Petr P Osicka Radim R Reseland Janne E JE Lyngstadaas Staale P SP Tiainen Hanna H Bousova Kristyna K Vondrasek Jiri J Sedlacek Radislav R Prochazka Jan J
Scientific reports 20230126 1
Highly specialized enamel matrix proteins (EMPs) are predominantly expressed in odontogenic tissues and diverged from common ancestral gene. They are crucial for the maturation of enamel and its extreme complexity in multiple independent lineages. However, divergence of EMPs occured already before the true enamel evolved and their conservancy in toothless species suggests that non-canonical functions are still under natural selection. To elucidate this hypothesis, we carried out an unbiased, com ...[more]