Development and validation of a four-dimensional registration technique for DCE breast MRI.

ABSTRACT:

Background

Patient motion can degrade image quality of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) due to subtraction artifacts. By objectively and subjectively assessing the impact of principal component analysis (PCA)-based registration on pretreatment DCE-MRIs of breast cancer patients, we aim to validate four-dimensional registration for DCE breast MRI.

Results

After applying a four-dimensional, PCA-based registration algorithm to 154 pretreatment DCE-MRIs of histopathologically well-described breast cancer patients, we quantitatively determined image quality in unregistered and registered images. For subjective assessment, we ranked motion severity in a clinical reading setting according to four motion categories (0: no motion, 1: mild motion, 2: mode

SUBMITTER: Mattusch C 

PROVIDER: S-EPMC9880129 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature