Early neurological deterioration in patients with acute ischemic stroke: a prospective multicenter cohort study.

ABSTRACT:

Background

There is still no precise knowledge of the causes of progression in patients with acute ischemic stroke (AIS), and we are unable to predict patients at risk.

Objective

To explore the frequency, predictive factors, and the prognosis of early neurological deterioration (END) in patients with AIS.

Methods

In this prospective multicenter observational study, we assessed patients with AIS admitted to 18 hospitals in Henan, China. We defined END as an increase of ⩾2 points in total National Institutes of Health Stroke Scale (NIHSS) score or ⩾1 point in the motor items of the NIHSS within 7 days after admission. Risk factors were analyzed using multivariate logistic regression models. Prognosis was evaluated using the modified Rankin Scale (mRS), with poor prognos

SUBMITTER: Liu H 

PROVIDER: S-EPMC9880581 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature