Treatment preferences in relation to fatigue of patients with relapsing multiple sclerosis: A discrete choice experiment.

ABSTRACT:

Background

Treatment decisions for multiple sclerosis (MS) are influenced by many factors such as disease symptoms, comorbidities, and tolerability.

Objective

To determine how much relapsing MS patients were willing to accept the worsening of certain aspects of their MS in return for improvements in symptoms or treatment convenience.

Methods

A web-based discrete choice experiment (DCE) was conducted in patients with relapsing MS. Multinomial logit models were used to estimate relative attribute importance (RAI) and to quantify attribute trade-offs.

Results

The DCE was completed by 817 participants from the US, the UK, Poland, and Russia. The most valued attributes of MS therapy to participants were effects on physical fatigue (RAI = 22.3%), cognitive fatigue (R

SUBMITTER: Tervonen T 

PROVIDER: S-EPMC9880588 | biostudies-literature | 2023 Jan-Mar

REPOSITORIES: biostudies-literature