Naturalistic Sleep Patterns are Linked to Global Structural Brain Aging in Adolescence.

ABSTRACT:

Purpose

We examined whether interindividual differences in naturalistic sleep patterns correlate with any deviations from typical brain aging.

Methods

Our sample consisted of 251 participants without current psychiatric diagnoses (9-25 years; mean [standard deviation] = 17.4 ± 4.52 yr; 58% female) drawn from the Neuroimaging and Pediatric Sleep Databank. Participants completed a T1-weighted structural magnetic resonance imaging scan and 5-7 days of wrist actigraphy to assess naturalistic sleep patterns (duration, timing, continuity, and regularity). We estimated brain age from extracted structural magnetic resonance imaging indices and calculated brain age gap (estimated brain age-chronological age). Robust regressions tested cross-sectional associations between brain age ga

SUBMITTER: Soehner AM 

PROVIDER: S-EPMC9881228 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature