New Coprescription of Opioids and Benzodiazepines and Mortality Among Veterans Affairs Patients With Posttraumatic Stress Disorder.

ABSTRACT:

Background

Opioids and benzodiazepines are commonly coprescribed medications. The mortality risk associated with their concurrent use is unknown.

Objective

To estimate the all-cause mortality risk for patients newly prescribed opioids and benzodiazepines concurrently relative to patients prescribed benzodiazepines only, opioids only, or neither medication.

Methods

This propensity score-matched, retrospective, cohort study included 17,476 patients receiving Veterans Affairs (VA) health care between October 1, 2009, and September 30, 2011, and diagnosed with posttraumatic stress disorder identified using ICD-9-CM code 309.81. One-year total and cause-specific mortality was assessed by hazard ratios and subhazard ratios, adjusted for propensity score, age, baseline psych

SUBMITTER: Hawkins EJ 

PROVIDER: S-EPMC9881598 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature