Age-Stratified Model to Assess Health Outcomes of COVID-19 Vaccination Strategies, Ghana.

ABSTRACT: We assessed the effect of various COVID-19 vaccination strategies on health outcomes in Ghana by using an age-stratified compartmental model. We stratified the population into 3 age groups: <25 years, 25-64 years, and ≥65 years. We explored 5 vaccination optimization scenarios using 2 contact matrices, assuming that 1 million persons could be vaccinated in either 3 or 6 months. We assessed these vaccine optimization strategies for the initial strain, followed by a sensitivity analysis for the Delta variant. We found that vaccinating persons <25 years of age was associated with the lowest cumulative infections for the main matrix, for both the initial strain and the Delta variant. Prioritizing the elderly (≥65 years of age) was associated with the lowest cumulative deaths for both strains i

SUBMITTER: Ofori SK 

PROVIDER: S-EPMC9881782 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature