Light and temperature regulate m ⁶ A-RNA modification to regulate growth in plants.

ABSTRACT: N6-methyladenosine is a highly dynamic, abundant mRNA modification which is an excellent potential mechanism for fine tuning gene expression. Plants adapt to their surrounding light and temperature environment using complex gene regulatory networks. The role of m ⁶ A in controlling gene expression in response to variable environmental conditions has so far been unexplored. Here, we map the transcriptome-wide m ⁶ A landscape under various light and temperature environments. Identified m ⁶ A-modifications show a highly specific spatial distribution along transcripts with enrichment occurring in 5'UTR regions and around transcriptional end sites. We show that the position of m ⁶ A modifications on transcripts might influence cellular transcript loca

SUBMITTER: Artz O 

PROVIDER: S-EPMC9882139 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature