Synovial Fluid Inflammatory Profiles did not Differ between Isolated Anterior Cruciate Ligament and Multi-ligament Knee Injuries.

ABSTRACT:

Objective and design

The purpose of this study was to compare synovial concentrations of pro- and anti-inflammatory cytokines between multiple-ligament knee injured (MLKI) and anterior cruciate ligament (ACL)-injured patients.

Subjects

14 patients with MLKI and 10 patients with isolated ACL injury.

Methods

Synovial fluid was aspirated from the operative knee at the time of surgery and the concentrations of pro- and anti-inflammatory markers in the synovial fluid were determined. Structures injured, the time between injury and surgery, and demographic factors were collected. Linear regressions were used to determine the association between injury pattern and synovial inflammatory markers when controlling for age, BMI, and time between injury and surgery.

Results

SUBMITTER: Jacobs CA 

PROVIDER: S-EPMC9882650 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature