Gestational exposure to organophosphate esters and infant anthropometric measures in the first 4 weeks after birth.

ABSTRACT:

Background

Few studies have examined whether gestational exposure to organophosphate esters (OPEs), widely used chemicals with potential endocrine-disrupting potency and developmental toxicity, is associated with impaired infant growth.

Methods

We analyzed data from 329 mother-infant pairs in the Health Outcomes and Measures of the Environment (HOME) Study (2003-2006, Cincinnati, Ohio, USA). We quantified concentrations of four OPE metabolites in maternal urine collected at 16 and 26 weeks of gestation, and at delivery. We calculated z-scores using 2006 World Health Organization (WHO) child growth standards for the 4-week anthropometric measures (weight, length, and head circumference), the ponderal index, and weekly growth rates. We used multiple informant models to examine

SUBMITTER: Yang W 

PROVIDER: S-EPMC9883112 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature