Estimating the Relationship Between EQ-5D-5L and EQ-5D-3L: Results from a UK Population Study.

ABSTRACT:

Objectives

The aim of this study was to estimate the relationship between EQ-5D-3L and EQ-5D-5L, in both directions, using a single model.

Methods

An online survey containing both variants of EQ-5D, with randomised ordering, was administered to a large UK sample in 2020. A joint statistical model of the ten EQ-5D responses (five at 5L, five at 3L), using a multi-equation ordinal regression framework was estimated. The joint model ensures mappings in either direction are fully consistent with the information in the sample and satisfy Bayes' rule. Three extensions enhance model flexibility: a copula specification allows differing degrees of correlation between the 3L and 5L responses at the upper and lower extremes of health; a normal mixture residual distribution gives flexib

SUBMITTER: Hernandez Alava M 

PROVIDER: S-EPMC9883358 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature