Kidney disease in very long-term survivors of Wilms tumor: A nationwide cohort study with sibling controls.

ABSTRACT:

Background

Survival after Wilms tumor has significantly increased and focus on late effects has become increasingly important. However, knowledge about long-term renal function in survivors of Wilms tumor is missing. Our aim was to investigate evidence of kidney disease in 20- or more-year survivors of Wilms tumor in a clinical setting, with siblings as comparisons.

Methods

In this cross-sectional study, we established a cohort of Danish 20-plus-year survivors of Wilms tumor and siblings as controls. Participants answered a comprehensive health questionnaire supplemented by measurements of estimated glomerular filtration rate (eGFR), urine albumin-to-creatinine ratio, and blood pressure and were categorized according to the chronic kidney disease classification. Multiple lin

SUBMITTER: Hogsholt S 

PROVIDER: S-EPMC9883410 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature