Dysbiotic microbiome variation in colorectal cancer patients is linked to lifestyles and metabolic diseases.

ABSTRACT:

Background

Differences in the composition and diversity of the gut microbial communities among individuals are influenced by environmental factors. However, there is limited research on factors affecting microbiome variation in colorectal cancer patients, who display lower inter-individual variations than that of healthy individuals. In this study, we examined the association between modifiable factors and the microbiome variation in colorectal cancer patients.

Methods

A total of 331 colorectal cancer patients who underwent resection surgery at the Department of Surgery, Seoul National University Hospital between October 2017 and August 2019 were included. Fecal samples from colorectal cancer patients were collected prior to the surgery. Variations in the gut microbiome amon

SUBMITTER: Hoang T 

PROVIDER: S-EPMC9883847 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature