Lipid biomarkers that reflect postoperative recurrence risk in lung cancer patients who smoke: a case-control study.

ABSTRACT:

Background

The risk of postoperative recurrence is higher in lung cancer patients who smoke than non-smokers. However, objective evaluation of the postoperative recurrence risk is difficult using conventional pathological prognostic factors because of their lack of reproducibility. Consequently, novel objective biomarkers that reflect postoperative risk in lung cancer patients who smoke must be identified. Because cigarette smoking and oncogenesis alter lipid metabolism in lung tissue, we hypothesized that the lipid profiles in lung cancer tissues are influenced by cigarette smoking and can reflect the postoperative recurrence risk in smoking lung cancer patients. This study aimed to identify lipid biomarkers that reflect the smoking status and the postoperative recurrence risk.

SUBMITTER: Takanashi Y 

PROVIDER: S-EPMC9883920 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature