Epidemiological, clinical, and household transmission characteristics of children and adolescents infected with SARS-CoV-2 Omicron variant in Shanghai, China: a retrospective, multicenter observational study.

ABSTRACT:

Objectives

To describe the epidemiological, clinical, and household transmission characteristics of pediatric COVID-19 cases in Shanghai, China.

Methods

Pediatric patients with COVID-19 hospitalized in Shanghai from March-May 2022 were enrolled in this retrospective, multicenter cohort study. The symptoms and the risk factors associated with disease severity were analyzed.

Results

In total, 2620 cases (age range, 24 days-17 years) were enrolled in this study. Of these, 1011 (38.6%) were asymptomatic, whereas 1415 (54.0%), 190 (7.3%), and 4 (0.2%) patients developed mild, moderate, and severe illnesses, respectively. Household infection rate was negatively correlated with household vaccination coverage. Children aged 0-3 years, those who are unvaccinated, those with un

SUBMITTER: Liu Y 

PROVIDER: S-EPMC9884399 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature