Psilocybin-assisted therapy improves psycho-social-spiritual well-being in cancer patients.

ABSTRACT:

Background

While psychedelics have been shown to improve psycho-spiritual well-being, the underlying elements of this change are not well-characterized. The NIH-HEALS posits that psycho-social-spiritual change occurs through the factors of Connection, Reflection & Introspection, and Trust & Acceptance. This study aimed to evaluate the changes in NIH-HEALS scores in a cancer population with major depressive disorder undergoing psilocybin-assisted therapy.

Methods

In this Phase II, single-center, open label trial, 30 cancer patients with major depressive disorder received a fixed dose of 25 mg of psilocybin. Participants underwent group preparation sessions, simultaneous psilocybin treatment administered in adjacent rooms, and group integration sessions, along with individual

SUBMITTER: Shnayder S 

PROVIDER: S-EPMC9884542 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature