Possibility of averting cytokine storm in SARS-COV 2 patients using specialized pro-resolving lipid mediators.

ABSTRACT: Fatal "cytokine storms (CS)" observed in critically ill COVID-19 patients are consequences of dysregulated host immune system and over-exuberant inflammatory response. Acute respiratory distress syndrome (ARDS), multi-system organ failure, and eventual death are distinctive symptoms, attributed to higher morbidity and mortality rates among these patients. Consequent efforts to save critical COVID-19 patients via the usage of several novel therapeutic options are put in force. Strategically, drugs being used in such patients are dexamethasone, remdesivir, hydroxychloroquine, etc. along with the approved vaccines. Moreover, it is certain that activation of the resolution process is important for the prevention of chronic diseases. Until recently Inflammation resolution was considered a passi

SUBMITTER: Yasmeen N 

PROVIDER: S-EPMC9884647 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature