The association between diabetes status and latent-TB IGRA levels from a cross-sectional study in eastern China.

ABSTRACT:

Background

There is a debate regarding the sensitivity of the QuantiFERON-TB Gold In-Tube (QFT) among people with diabetes, and prior studies have shown heterogeneous results. We evaluated whether the QFT TB antigen was modified among persons with differing diabetes status and other related risk factors.

Methods

A cross-sectional study of 5,302 people was conducted to screen latent tuberculosis infection (LTBI) in eastern China. The QFT assay was performed as an indicator of LTBI. Fasting plasma glucose (FPG) was collected from each participant; the definition of diabetes followed the guidelines from the American Diabetes Association. Participants were classified into normoglycemia, prediabetes, undiagnosed diabetes, and previously diagnosed diabetes to evaluate the relation

SUBMITTER: Chen C 

PROVIDER: S-EPMC9884689 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature