Shift in the submucosal microbiome of diseased peri-implant sites after non-surgical mechanical debridement treatment.

ABSTRACT:

Objectives

The object of this prospective study was to assess the submucosal microbiome shifts in diseased peri-implant sites after non-surgical mechanical debridement therapy.

Materials and methods

Submucosal plaques were collected from 14 healthy implants and 42 diseased implants before and eight weeks after treatment in this prospective study. Mechanical debridement was performed using titanium curettes, followed by irrigation with 0.2% (w/v) chlorhexidine. Subsequently, 16S rRNA gene sequencing was used to analyze the changes in the submucosal microbiome before and after the non-surgical treatment.

Results

Clinical parameters and the submucosal microbiome were statistically comparable before and after mechanical debridement. The Alpha diversity decreased significa

SUBMITTER: Sun F 

PROVIDER: S-EPMC9884694 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature