Protocol for a MULTI-centre feasibility study to assess the use of ^99mTc-sestaMIBI SPECT/CT in the diagnosis of kidney tumours (MULTI-MIBI study).

ABSTRACT:

Introduction

The incidence of renal tumours is increasing and anatomic imaging cannot reliably distinguish benign tumours from renal cell carcinoma. Up to 30% of renal tumours are benign, with oncocytomas the most common type. Biopsy has not been routinely adopted in many centres due to concerns surrounding non-diagnostic rate, bleeding and tumour seeding. As a result, benign masses are often unnecessarily surgically resected. ^99mTc-sestamibi SPECT/CT has shown high diagnostic accuracy for benign renal oncocytomas and other oncocytic renal neoplasms of low malignant potential in single-centre studies. The primary aim of MULTI-MIBI is to assess feasibility of a multicentre study of ^99mTc-sestamibi SPECT/CT against a reference standard of histopathology from sur

SUBMITTER: Warren H 

PROVIDER: S-EPMC9884914 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature