Early urine output monitoring in very preterm infants to predict in-hospital neonatal outcomes: a bicentric retrospective cohort study.

ABSTRACT:

Objective

To evaluate whether urine output (UO), rarely assessed in the literature, is associated with relevant neonatal outcomes in very preterm infants, and which UO threshold may be the most clinically relevant.

Design

Retrospective cohort study.

Setting

Two Level IV neonatal intensive care units.

Patients

Very preterm infants born between 24^0/7 and 29^6/7 weeks of gestation documented with eight UO measurements per day between postnatal day 1 and day 7.

Main outcome measures

Composite outcome defined as death before discharge, or moderate to severe bronchopulmonary dysplasia, or severe brain lesions. The association between this outcome and UO was studied using several UO thresholds.

Results

Among 532 infants studied, UO <

SUBMITTER: De Mul A 

PROVIDER: S-EPMC9884922 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature