Concomitant preoperative airflow obstruction confers worse prognosis after trans-thoracic surgery for esophageal cancer.

ABSTRACT:

Background

Airflow obstruction is a critical element of chronic airway diseases. This study aimed to evaluate the impact of preoperative airflow obstruction on the prognosis of patients following surgery for esophageal carcinoma.

Methods

A total of 821 esophageal cancer patients were included and classified into two groups based on whether or not they had preoperative airflow obstruction. Airflow obstruction was defined as a forced expiration volume in the first second (FEV₁)/forced vital capacity (FVC) ratio below the lower limit of normal (LLN). A retrospective analysis of the impact of airflow obstruction on the survival of patients with esophageal carcinoma undergoing esophagectomy was performed.

Results

Patients with airflow obstruction (102/821, 12.4%

SUBMITTER: Lang K 

PROVIDER: S-EPMC9885207 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature