Exploration and comparison of molecular mechanisms across diseases using MINERVA Net.

ABSTRACT: Protein function is often interpreted using molecular interaction diagrams, encoding roles a given protein plays in various molecular mechanisms. Information about disease-related mechanisms can be inferred from disease maps, knowledge repositories containing manually constructed systems biology diagrams. Disease maps hosted on the Molecular Interaction Network VisuAlization (MINERVA) Platform are individually accessible through a REST API interface of each instance, making it challenging to systematically explore their contents. To address this challenge, we introduce the MINERVA Net web service, a repository of open-access disease maps allowing users to publicly share minimal information about their maps. The MINERVA Net repository provides REST API endpoints of particular disease maps,

SUBMITTER: Gawron P 

PROVIDER: S-EPMC9885449 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature