Dearomatization of benzopyrylium triflates with sulfoxonium ylides.

ABSTRACT: Benzopyrylium triflates react with sulfoxonium ylides to give rise to cyclopropanated products in up to 90% yield as a single diastereomer. The cyclopropanated products can easily undergo acid-mediated ring-expansion to afford benzo[b]oxepines. Control over the absolute stereochemistry of the process is possible when the reaction is executed under the influence of a suitable anion-binding catalyst.

SUBMITTER: Leveille AN 

PROVIDER: S-EPMC9885494 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature