The methanogen core and pangenome: conservation and variability across biology's growth temperature extremes.

ABSTRACT: Temperature is a key variable in biological processes. However, a complete understanding of biological temperature adaptation is lacking, in part because of the unique constraints among different evolutionary lineages and physiological groups. Here we compared the genomes of cultivated psychrotolerant and thermotolerant methanogens, which are physiologically related and span growth temperatures from -2.5°C to 122°C. Despite being phylogenetically distributed amongst three phyla in the archaea, the genomic core of cultivated methanogens comprises about one-third of a given genome, while the genome fraction shared by any two organisms decreases with increasing phylogenetic distance between them. Increased methanogenic growth temperature is associated with reduced genome size, and thermotoler

SUBMITTER: Prondzinsky P 

PROVIDER: S-EPMC9886072 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature