Low-dose aspirin in the prevention of preeclampsia in twin pregnancies: A real-world study.

ABSTRACT:

Background

The use of low-dose aspirin for women with twin pregnancies remains controversial. This study was to describe the frequency of preeclampsia and aspirin use in twin pregnancies in real practice.

Methods

This retrospective cohort study based on real-world data was conducted in the Obstetrics and Gynecology Hospital of Fudan University between 2013 and 2020. Women with twin pregnancies who received prenatal care before 20 weeks of gestational age were included. They were divided into those using low-dose aspirin (LDA group) and those not using aspirin group (N-LDA group). The primary outcome was the frequency of preeclampsia, and secondary outcomes included early-onset and preterm mild and severe preeclampsia.

Results

A total of 2,946 women had twin pregnancie

SUBMITTER: Zhou Q 

PROVIDER: S-EPMC9886671 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature