Carotid disease, cognition, and aging: time to redefine asymptomatic disease?

ABSTRACT: There is an increasing appreciation of the vascular contributions in the development of age-related cognitive impairment and dementia^1,2. Identifying risk and maintaining cognitive health for successful aging is ever relevant in our aging population. Carotid disease, a well-established risk factor for stroke and often a harbinger of other vascular disease states, is also emerging as another vascular risk factor for age-related cognitive decline. When combined with vascular risk factors, the incidence of age-related carotid disease can be as high as 70%^3,4. Historically, carotid disease has been dichotomized into two large groups in trial design, outcome measurements, and treatment decisions: symptomatic and asymptomatic carotid artery stenosis. The dichotomous distinc

SUBMITTER: Lineback CM 

PROVIDER: S-EPMC9886762 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature