Improvement of halitosis by probiotic bacterium Weissella cibaria CMU: A randomized controlled trial.

ABSTRACT: Several in vitro and in vivo studies have evaluated the effect of probiotics on oral health; however, human clinical studies are still limited. Therefore, this study aimed to examine the effects of Weissella cibaria Chonnam Medical University (CMU)-containing tablets on halitosis. This randomized, double-blinded, placebo-controlled study included 100 adults with halitosis (age, 20-70 years). The participants were randomly assigned to the test group (n = 50) and control group (n = 50). One tablet [1 × 10⁸ colony forming units (CFU)/tablet] was to be taken each day over 8 weeks. The concentrations of volatile sulfur compounds (VSCs), bad breath improvement scores, and oral colonization of W. cibaria were measured. Psychosocial indicators i

SUBMITTER: Han HS 

PROVIDER: S-EPMC9886871 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature