Addressing the pervasive scarcity of structural annotation in eukaryotic algae.

ABSTRACT: Despite a continuous increase in algal genome sequencing, structural annotations of most algal genome assemblies remain unavailable. This pervasive scarcity of genome annotation has restricted rigorous investigation of these genomic resources and may have precipitated misleading biological interpretations. However, the annotation process for eukaryotic algal species is often challenging as genomic resources and transcriptomic evidence are not always available. To address this challenge, we benchmark the cutting-edge gene prediction methods that can be generalized for a broad range of non-model eukaryotes. Using the most accurate methods selected based on high-quality algal genomes, we predict structural annotations for 135 unannotated algal genomes. Using previously available genomic data

SUBMITTER: Kwon T 

PROVIDER: S-EPMC9886943 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature