Amygdala but not hippocampal damage associated with smaller social network size.

ABSTRACT: Social network size has been associated with complex socio-cognitive processes (e.g., memory, perspective taking). Supporting this idea, recent neuroimaging studies in healthy adults have reported a relationship between social network size and brain volumes in regions related to memory and social cognition (e.g., hippocampus, amygdala). Lesion-deficit studies in neurological patients are rare and have been inconclusive due to differences in participant sampling and measurement. The present study uses a multiple case study approach. We investigated patients with focal damage to the hippocampus and/or amygdala (two neural structures thought to be critical for social networks), and examined the patients' social network size, loneliness, and life satisfaction relative to a non-injured comparis

SUBMITTER: Beadle JN 

PROVIDER: S-EPMC9887793 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature