Health economic evidence for adjuvant chemotherapy in stage II and III colon cancer: a systematic review.

ABSTRACT:

Objective

The aims of this study was to appraise the health economic evidence for adjuvant chemotherapy (AC) strategies in stage II and III colon cancer (CC) and identify gaps in the available evidence that might inform further research.

Method

A systematic review of published economic evaluations was undertaken. Four databases were searched and full-text publications in English were screened for inclusion. A narrative synthesis was performed to summarise the evidence.

Results

Thirty-eight studies were identified and stratified by cancer stage and AC strategy. The majority (89%) were full economic evaluations considering both health outcomes, usually measured as quality-adjusted life years (QALYs), and costs. AC was found to be cost-effective compared to no AC for bot

SUBMITTER: To YH 

PROVIDER: S-EPMC9887815 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature