A prediction model for the impact of environmental and genetic factors on cardiovascular events: development in a salt substitutes population.

ABSTRACT:

Background

Cardiovascular disease (CVD) has evolved into a serious public health issue that demands the use of suitable methods to estimate the risk of the disease. As a result, in a sample of individuals who completed a 3-year low-sodium salt or conventional salt intervention in a hypertensive environment, we constructed a 13-year cardiovascular (CV) event risk prediction model with a 10-year follow-up.

Methods

A Cox proportional hazards model was used to build a prediction model based on data from 306 participants who matched the inclusion criteria. Both the discriminating power and the calibration of the prediction models were assessed. The discriminative power of the prediction model was measured using the area under the curve (AUC). Brier scores and calibration plots we

SUBMITTER: Zhao D 

PROVIDER: S-EPMC9887817 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature