Diagnostic performance of optical coherence tomography macular ganglion cell inner plexiform layer and retinal nerve fiber layer thickness in glaucoma suspect and early glaucoma patients at St. Paul's hospital millennium medical college, Addis Ababa, Ethiopia.

ABSTRACT:

Purpose

To evaluate glaucoma diagnostic performance of ganglion cell inner plexiform layer and retinal nerve fiber layer parameters measured with cirrus HD optical coherence tomography (OCT).

Method

Total of 188 eyes were included in our study. 49 eyes of healthy controls, 70 glaucoma suspect eyes and 69 early glaucomatous eyes. Complete ophthalmic examination was done including visual field test (with Humphrey field analyzer) and OCT scanning of ganglion cell inner plexiform layer (GCIPL) and retinal nerve fiber layer (RNFL) in different quadrants. Sensitivity, specificity and area under the receiver operating characteristic curve (AUROC) of each parameter was calculated to provide diagnostic ability between normal controls, glaucoma suspects or early glaucoma.

Result

SUBMITTER: Abera A 

PROVIDER: S-EPMC9888678 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature