A novel shape-based approach to identify gestational age-adjusted growth patterns from birth to 11 years of age.

ABSTRACT: Child growth patterns assessment is critical to design public health interventions. However, current analytical approaches may overlook population heterogeneity. To overcome this limitation, we developed a growth trajectories clustering pipeline that incorporates a shape-respecting distance, baseline centering (i.e., birth-size normalized trajectories) and Gestational Age (GA)-correction to characterize shape-based child growth patterns. We used data from 3945 children (461 preterm) in the 2004 Pelotas Birth Cohort with at least 3 measurements between birth (included) and 11 years of age. Sex-adjusted weight-, length/height- and body mass index-for-age z-scores were derived at birth, 3 months, and at 1, 2, 4, 6 and 11 years of age (INTERGROWTH-21st and WHO growth standards). Growth traject

SUBMITTER: Lopez-Dominguez L 

PROVIDER: S-EPMC9889302 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature