Progression of lipase activity and pancreatic lipase immunoreactivity in dogs hospitalized for acute pancreatitis and correlation with clinical features.

ABSTRACT:

Background

Lipase activity and pancreatic lipase immunoreactivity (PLI) have not been compared in dogs hospitalized for acute pancreatitis (AP).

Objectives

To describe the progression of lipase activity and PLI, and correlations with clinicopathologic features in dogs with AP.

Animals

Thirty-nine dogs with AP based on clinical signs and lipase activity >350 U/L (reference interval [RI], 24-108 U/L).

Methods

Retrospective study. Lipase activity (LIPC Roche), PLI (SpecPL), and clinical signs were recorded daily. Admission (d1) data (clinical, laboratory, and ultrasound [US] findings), and clinical signs during hospitalization (d2-d3) were assessed for correlation with lipases.

Results

Median (range) duration of clinical signs before presentation was 2 days

SUBMITTER: Cueni C 

PROVIDER: S-EPMC9889606 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature