The Relationship between Delirium and Statin Use According to Disease Severity in Patients in the Intensive Care Unit.

ABSTRACT:

Objective

The aim of this study was to investigate the association between the use of statins and the occurrence of delirium in a large cohort of patients in the intensive care unit (ICU), considering disease severity and statin properties.

Methods

We obtained clinical and demographical information from 3,604 patients admitted to the ICU from January 2013 to April 2020. This included information on daily statin use and delirium state, as assessed by the Confusion Assessment Method for ICU. We used inverse probability of treatment weighting and categorized the patients into four groups based on the Acute Physiology and Chronic Health Evaluation II score (group 1: 0-10 - mild; group 2: 11-20 - mild to moderate; group 3: 21-30 - moderate to severe; group 4: > 30 - severe). We a

SUBMITTER: An JY 

PROVIDER: S-EPMC9889904 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature