Quantile regression to examine the association of air pollution with subclinical atherosclerosis in an adolescent population.

ABSTRACT:

Background

Air pollution has been associated with carotid intima-media thickness test (CIMT), a marker of subclinical atherosclerosis. To our knowledge, this is the first study to report an association between ambient air pollution and CIMT in a younger adolescent population.

Objective

To investigate the associations beyond standard mean regression by using quantile regression to explore if associations occur at different percentiles of the CIMT distribution.

Methods

We measured CIMT cross-sectionally at the age of 16 years in 363 adolescents participating in the Dutch PIAMA birth cohort. We fit separate quantile regressions to examine whether the associations of annual averages of nitrogen dioxide (NO₂), fine particulate matter (PM_2.5), PM₂

SUBMITTER: Peralta AA 

PROVIDER: S-EPMC9890274 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature